Ravulizumab - ChemeGen 中国-全球抑制剂领导者 | 抑制剂-激动剂...

来自 : www.chemegen.com/h-pd-37...htm 发布时间：2021-03-26

信号通路Anti-infectionArenavirusBacterialCMVEnterovirusFilovirusFungalHBVHCVHIVHSVInfluenza VirusParasiteReverse TranscriptaseRSVSARS-CoVVirus ProteaseAntibody-drug Conjugate/ADC RelatedADC CytotoxinADC LinkerDrug-Linker Conjugates for ADCPROTAC-linker Conjugate for PACApoptosisApoptosisFKBPBcl-2 Familyc-MycCaspaseDAPKFerroptosisIAPMDM-2/p53PKDRIP kinaseSurvivinThymidylate SynthaseTNF ReceptorAutophagyAutophagyLRRK2MitophagyULKCell Cycle/DNA DamageAntifolateAPCATM/ATRAurora KinaseCasein KinaseCDKCheckpoint Kinase (Chk)CRISPR/Cas9DeubiquitinaseDNA Alkylator/CrosslinkerDNA-PKDNA/RNA SynthesisEukaryotic Initiation Factor (eIF)G-quadruplexHaspin KinaseHDACHSPIRE1KinesinLIM Kinase (LIMK)Microtubule/TubulinMps1Nucleoside Antimetabolite/Analogp97PAKPARPPERKPolo-like Kinase (PLK)PPARRAD51ROCKSirtuinSRPKTelomeraseTOPKTopoisomeraseWee1CytoskeletonArp2/3 ComplexDynaminGap Junction ProteinIntegrinKinesinMicrotubule/TubulinMps1MyosinPAKEpigeneticsAMPKAurora KinaseDNA MethyltransferaseEpigenetic Reader DomainHDACHistone AcetyltransferaseHistone DemethylaseHistone MethyltransferaseJAKMicroRNAPARPPKCProtein Arginine DeiminaseTAM ReceptorSirtuinGPCR/G Protein5-HT ReceptorAdenosine ReceptorAdenylate CyclaseAdiponectin ReceptorAdrenergic ReceptorAngiotensin ReceptorBombesin ReceptorBradykinin ReceptorCannabinoid ReceptorCaSRCCRCGRP ReceptorCholecystokinin ReceptorCRFRCXCRDopamine ReceptorEBI2/GPR183Endothelin ReceptorGHSRGlucagon ReceptorGlucocorticoid ReceptorGNRH ReceptorGPCR19GPR109AGPR119GPR120GPR139GPR40GPR55GPR84Guanylate CyclaseHistamine ReceptorImidazoline ReceptorLeukotriene ReceptorLPL ReceptormAChRMCHR1 (GPR24)Melanocortin ReceptorMelatonin ReceptormGluRMotilin ReceptorNeurokinin ReceptorNeuropeptide Y ReceptorNeurotensin ReceptorOpioid ReceptorOrexin Receptor (OX Receptor)Oxytocin ReceptorP2Y ReceptorProstaglandin ReceptorProtease-Activated Receptor (PAR)RasRGS ProteinSigma ReceptorSomatostatin ReceptorTSH ReceptorUrotensin ReceptorVasopressin ReceptorImmunology/InflammationArginaseAryl Hydrocarbon ReceptorCCRComplement SystemCOXCXCRFLAPHistamine ReceptorIFNARInterleukin RelatedIRAKMyD88NO SynthaseNOD-like Receptor (NLR)PD-1/PD-L1PGE synthaseSalt-inducible Kinase (SIK)SPHKSTINGThrombopoietin ReceptorToll-like Receptor (TLR)CD73Reactive Oxygen SpeciesGalectinJAK/STAT SignalingEGFRJAKPimSTATMAPK/ERK PathwayERKJNKKLFMAP3KMAP4KMAPKAPK2 (MK2)MEKMixed Lineage KinaseMNKp38 MAPKRafRibosomal S6 Kinase (RSK)Membrane Transporter/Ion ChannelATP SynthaseBCRPCalcium ChannelCFTRChloride ChannelCRAC ChannelCRM1EAAT2GABA ReceptorGlyTHCN ChanneliGluRMonoamine TransporterMonocarboxylate TransporterNa+/Ca2+ ExchangerNa+/HCO3- CotransporterNa+/K+ ATPasenAChRNKCCP-glycoproteinP2X ReceptorPotassium ChannelProton PumpSGLTSodium ChannelTRP ChannelURAT1Metabolic Enzyme/Protease15-PGDH5 alpha Reductase5-LipoxygenaseAcetyl-CoA CarboxylaseAcyltransferaseAdenosine DeaminaseAdenosine KinaseAldehyde Dehydrogenase (ALDH)Aldose ReductaseAminoacyl-tRNA SynthetaseAminopeptidaseAngiotensin-converting Enzyme (ACE)ArginaseATGLATP Citrate LyaseCarbonic AnhydraseCarboxypeptidaseCathepsinCETPCOMTCytochrome P450Dipeptidyl PeptidaseDopamine β-hydroxylaseDrug MetaboliteE1/E2/E3 EnzymeElastaseEndogenous MetaboliteEnolaseFAAHFABPFactor XaFarnesyl TransferaseFatty Acid Synthase (FAS)FXRGlucokinaseGSNORGutathione S-transferaseHCV ProteaseHexokinaseHIF/HIF Prolyl-HydroxylaseHIV IntegraseHIV ProteaseHMG-CoA Reductase (HMGCR)HSPIndoleamine 2,3-Dioxygenase (IDO)Isocitrate Dehydrogenase (IDH)Lactate DehydrogenaseLXRMAGLMineralocorticoid ReceptorMitochondrial MetabolismMMPNADPH OxidaseNamptNEDD8-activating EnzymeNeprilysinPAI-1PDHKPGC-1αPhosphatasePhosphodiesterase (PDE)PhospholipaseProcollagen C ProteinaseProteasomePyruvate KinaseRAR/RXRReninRORSer/Thr ProteaseSGKStearoyl-CoA Desaturase (SCD)ThrombinTryptophan HydroxylaseTyrosinaseXanthine OxidaseGlutaminaseGlutathione PeroxidaseNeuronal Signaling5-HT ReceptorAChEAdenosine KinaseAmyloid-βBeta-secretaseCaMKCGRP ReceptorCOMTDopamine ReceptorDopamine TransporterFAAHGABA ReceptorGlyTiGluRImidazoline ReceptormAChRMelanocortin ReceptorMelatonin ReceptorMonoamine OxidasenAChRNeurokinin ReceptorOpioid ReceptorSerotonin Transporterγ-secretaseNF-κBIKKKeap1-Nrf2MALT1NF-κBPI3K/Akt/mTORAktAMPKATM/ATRDNA-PKGSK-3MELKmTORPDK-1PI3KPI4KPIKfyvePTENPROTACE3 Ligase Ligand-Linker ConjugateLigand for E3 LigasePROTACPROTAC LinkerPROTAC-linker Conjugate for PACLigand for Target Protein for PROTACSNIPERTarget Protein Ligand-Linker ConjugateProtein Tyrosine Kinase/RTKAck1ALKBcr-AblBMX KinaseBtkc-Fmsc-Kitc-Met/HGFRDiscoidin Domain ReceptorDYRKEGFREphrin ReceptorFAKFGFRFLT3IGF-1RInsulin ReceptorIRAKItkPDGFRPKAPyk2ROSSrcSykTAM ReceptorTrk ReceptorVEGFRRETStem Cell/WntCasein KinaseERKGliGSK-3HedgehogHippo (MST)JAKNotchOct3/4PKAPorcupineROCKsFRP-1SmoSTATTGF-beta/SmadWntYAPβ-cateninγ-secretaseTGF-beta/SmadPKCROCKTGF-beta/SmadTGF-β ReceptorVitamin D RelatedVD/VDROthersAndrogen ReceptorAromataseEstrogen Receptor/ERRProgesterone ReceptorThyroid Hormone ReceptorOthersInhibitory AntibodiesCytokinesADCEpigenetic Reader Dom